概述：

      性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)(precocious puberty)是指(zhi)青春(chun)(chun)期(qi)提早(zao)(zao)(zao)(zao)出現(xian)(xian)即女性(xing)(xing)(xing)(xing)(xing)(xing)在8歲(sui)以(yi)前出現(xian)(xian)性(xing)(xing)(xing)(xing)(xing)(xing)腺(xian)增大和第(di)二性(xing)(xing)(xing)(xing)(xing)(xing)征，或者(zhe)在10歲(sui)之(zhi)前出現(xian)(xian)月(yue)經，男性(xing)(xing)(xing)(xing)(xing)(xing)在9歲(sui)以(yi)前發育按發病機(ji)制的不同(tong)，性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)一般(ban)可(ke)分為(wei)兩大類(lei)：促性(xing)(xing)(xing)(xing)(xing)(xing)腺(xian)激(ji)素釋放激(ji)素(GnRH)依(yi)賴性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)(真(zhen)性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu))和非(fei)GnRH依(yi)賴性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)(假性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu));前者(zhe)稱中樞性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)或完(wan)全性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)，后者(zhe)稱外周性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)此外，不完(wan)全性(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)熟(shu)(shu)，如單純(chun)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)發育單純(chun)性(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)(zao)(zao)現(xian)(xian)，有學者(zhe)歸(gui)入青春(chun)(chun)發育的變異(yi)類(lei)型。

      性早熟的分類：

　　性(xing)早熟(shu)大體分為真(zhen)性(xing)和(he)假性(xing)性(xing)早熟(shu)兩大類。

　　真性(xing)(xing)性(xing)(xing)早熟,與正常性(xing)(xing)成熟一(yi)樣，僅是提早發育。發育過程也按(an)正常次序相(xiang)繼出現(xian)，有排卵性(xing)(xing)月經周期和生育能(neng)力(li)。有報告在5-10歲兒(er)童發生妊娠(shen)，分娩者。體質性(xing)(xing)因(yin)素(su)，中樞(shu)神經系統病變，腎上腺性(xing)(xing)征綜合征治療后均有可能(neng)導(dao)致性(xing)(xing)早熟。

　　假性(xing)性(xing)早(zao)熟(shu)(shu)是(shi)指第二性(xing)征發(fa)育(yu)(yu)出現(xian)在卵巢發(fa)育(yu)(yu)前即可有生(sheng)殖器發(fa)育(yu)(yu)，發(fa)育(yu)(yu)，及腋毛(mao)生(sheng)長，而生(sheng)育(yu)(yu)能力(li)不提前，或有無排(pai)卵性(xing)月(yue)經。有時也可出現(xian)單一的性(xing)早(zao)熟(shu)(shu)現(xian)象(xiang)(xiang)，如單純早(zao)現(xian)或單純性(xing)發(fa)育(yu)(yu)過早(zao)。腎上腺(xian)皮(pi)質病變(bian)，皮(pi)質增生(sheng)常可造成(cheng)異性(xing)假性(xing)性(xing)早(zao)熟(shu)(shu)，表現(xian)為男(nan)性(xing)化，多毛(mao)，骨(gu)骼(ge)和肌肉(rou)發(fa)育(yu)(yu)，聲調改變(bian)，肥大，不發(fa)育(yu)(yu)等現(xian)象(xiang)(xiang)。

　　而有功能(neng)性卵巢(chao)腫(zhong)(zhong)瘤者(zhe)，因分泌(mi)大量雌激(ji)素，造成生殖道及第二性征迅速(su)發育(yu)，發生月經樣(yang)出(chu)血，但無排(pai)卵。手術切除腫(zhong)(zhong)瘤后(hou)，癥狀迅速(su)消失。