概述

      (precocious puberty)是指(zhi)青(qing)春期提早(zao)(zao)出(chu)現(xian)即(ji)女性(xing)(xing)(xing)(xing)(xing)(xing)(xing)在(zai)8歲以前(qian)出(chu)現(xian)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)腺增大(da)和第二性(xing)(xing)(xing)(xing)(xing)(xing)(xing)征，或者在(zai)10歲之前(qian)出(chu)現(xian)，男(nan)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)在(zai)9歲以前(qian)發(fa)育(yu)按(an)發(fa)病機制的不(bu)同，性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)一般可(ke)分為兩大(da)類：促性(xing)(xing)(xing)(xing)(xing)(xing)(xing)腺激素釋(shi)放激素(GnRH)依賴性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)(真性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu))和非GnRH依賴性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)(假(jia)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu));前(qian)者稱中樞性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)或完全(quan)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)，后者稱外周性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)此外，不(bu)完全(quan)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)熟(shu)(shu)(shu)，如單純性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)發(fa)育(yu)單純性(xing)(xing)(xing)(xing)(xing)(xing)(xing)早(zao)(zao)現(xian)，有學者歸(gui)入(ru)青(qing)春發(fa)育(yu)的變異類型(xing)。

　  詳細完整(zheng)的病史，并包括性(xing)(xing)(xing)征(zheng)發(fa)育(yu)，陰道(dao)出血(xue)情況(kuang)，有(you)無(wu)服內(nei)分泌(mi)藥物(wu)等。用(yong)放射性(xing)(xing)(xing)免疫法測定血(xue)中促卵(luan)泡成熟(shu)激素FSH及LH有(you)助于區別真假性(xing)(xing)(xing)性(xing)(xing)(xing)早(zao)熟(shu)。體質性(xing)(xing)(xing)性(xing)(xing)(xing)早(zao)熟(shu)者，可有(you)卵(luan)巢增大，有(you)囊性(xing)(xing)(xing)變(bian)。懷疑(yi)腎上腺(xian)皮質疾患，可作(zuo)腺(xian)后壁充(chong)氣造(zao)影。頭(tou)顱的正側位像，觀察蝶鞍大小以除外腫(zhong)瘤等。

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